The Cell: A Molecular Approach, Second Edition

نویسنده

  • James Park
چکیده

The field of cell biology is changing so rapidly that cell textbooks often face obsolescence even before hitting the shelves. In response, some authors attempt to cope with explosion in cellular knowledge by including as many mechanisms and details as possible, which may satisfy the discriminating technical user who wants the most current findings. However, for the beginning student, the lucent and concise explanations of the general concepts in the second edition of The Cell: A Molecular Approach, published in 2000, offers a great course text for an introductory cell biology course. The strength of Cooper's text is found in its coherent voice that is often found in single-author books. In the field of cell biology, specialization is stressed so it is not uncommon to find textbooks written by multiple authors. Although the multi-author approach offers an expert view on individual subjects, it sometimes lacks the interconnections that a single talented author may gracefully make. Compared to the first edition, the second edition of The Cell retains the organization , themes, and special features of the original, but it has been completely updated in major areas of scientific progress, including: genome analysis; chromatin and transcription; nuclear transport; protein sorting and trafficking; signal trans-duction; the cell cycle; and programmed cell death. However, when comparing the second edition of The Cell with books such as Lodish's Molecular Biology of the Cell, it becomes clear that advanced students , even those taking an introductory biology course, The Cell lacks the depth and detail that an exacting student may demand. The text's lack of depth may leave some students with unanswered questions. Perhaps the book may be best complemented with a good molecular biology textbook. The extra explanations can make up for the missing depth of Cooper's text. Finally, many other cell biology textbooks offer accompanying CD-ROMs that animate the processes that govern life. Specifically, the use of Flash-enabled ani-mations that would bring to life The Cell's clear colorful and diagrams would be a definite welcome supplement to the next edition of The Cell.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Culture of Animal Cells: A Manual of Basic Technique

The field of cell biology is changing so rapidly that cell textbooks often face obsolescence even before hitting the shelves. In response, some authors attempt to cope with explosion in cellular knowledge by including as many mechanisms and details as possible, which may satisfy the discriminating technical user who wants the most current findings. However, for the beginning student, the lucent...

متن کامل

CRISPR/Cas9, a new approach to successful knockdown of ABCB1/P-glycoprotein and reversal of chemosensitivity in human epithelial ovarian cancer cell line

Objective(s): Multidrug resistance (MDR) is a major obstacle in the successful chemotherapy of ovarian cancer. Inhibition of P-glycoprotein (P-gp), a member of ATP-binding cassette (ABC) transporters, is a well-known strategy to overcome MDR in cancer. The aim of this study was to investigate the efficiency and ability of CRISPR/Cas9 genome editing technology to knockdown ABCB1 gene expression ...

متن کامل

Effect of Cold Atmospheric Plasma on Gene Expression and Methylation of Genes Involved in Colorectal Cancer

Background and purpose: Colorectal cancer (CRC) is ranked as the second most common cancer in men and the third most common cancer in women worldwide. Routine treatments have many side effects and little efficiency. The aim of this study was to investigate the effects of Cold Atmospheric Plasma (CAP) on epigenetic changes of some genes involved in CRC progression. Materials and methods: Prolif...

متن کامل

Closed-form Molecular Mechanics Formulations for the 3D Local Buckling and 2D Effective Young’s Modulus of the Nanosheets

A closed form three-dimensional solution is presented for determination of the local buckling (cell buckling) load of the nanosheets. Moreover, an expression is proposed for the effective 2D Young’s modulus of the unit cell of the nanosheet. In this regard, a three-dimensional efficient space-frame-like geometrical model with angular and extensional compliances is considered to investigate stab...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Yale Journal of Biology and Medicine

دوره 74  شماره 

صفحات  -

تاریخ انتشار 2001